Integrative priming occurs rapidly and uncontrollably during lexical processing

Lexical priming, whereby a prime word facilitates recognition of a related target word (e.g., nurse ? doctor), is typically attributed to association strength, semantic similarity, or compound familiarity. Here, the authors demonstrate a novel type of lexical priming that occurs among unassociated, dissimilar, and unfamiliar concepts (e.g., horse ? doctor). Specifically, integrative priming occurs when a prime word can be easily integrated with a target word to create a unitary representation. Across several manipulations of timing (stimulus onset asynchrony) and list context (relatedness proportion), lexical decisions for the target word were facilitated when it could be integrated with the prime word. Moreover, integrative priming was dissociated from both associative priming and semantic priming but was comparable in terms of both prevalence (across participants) and magnitude (within participants). This observation of integrative priming challenges present models of lexical priming, such as spreading activation, distributed representation, expectancy, episodic retrieval, and compound cue models. The authors suggest that integrative priming may be explained by a role activation model of relational integration

MRC B0319-454: Probing the large-scale structure with a giant radio galaxy

We present an investigation of the relationships between the radio properties of a giant radio galaxy MRC B0319-454 and the surrounding galaxy distribution with the aim of examining the influence of intergalactic gas and gravity associated with the large-scale structure on the evolution in the radio morphology. Our new radio continuum observations of the radio source, with high surface brightness sensitivity, images the asymmetries in the megaparsec-scale radio structure in total intensity and polarization. We compare these with the 3-D galaxy distribution derived from galaxy redshift surveys. Galaxy density gradients are observed along and perpendicular to the radio axis: the large-scale structure is consistent with a model wherein the galaxies trace the ambient intergalactic gas and the evolution of the radio structures are ram-pressure limited by this associated gas. Additionally, we have modeled the off-axis evolution of the south-west radio lobe as deflection of a buoyant jet backflow by a transverse gravitational field: the model is plausible if entrainment is small. The case study presented here is a demonstration that giant radio galaxies may be useful probes of the warm-hot intergalactic medium believed to be associated with moderately over dense galaxy distributions.Comment: 27 pages, 15 figures, accepted for publication in MNRA

The fisheye of the comet interceptor's EnVisS camera

Entire Visible Sky (EnVisS) camera is one of the payload proposed for the ESA selected F-Class mission Comet Interceptor. The main aim of the mission is the study of a dynamic new comet, or an interstellar object, entering the inner solar system for the first time. The Comet Interceptor mission is conceived to be composed of three spacecraft: a parent spacecraft A and two, spacecraft B1 and B2, dedicated to a close and risky fly-by. EnVisS will be mounted on spacecraft B2, which is foreseen to be spin-stabilized. The EnVisS camera is designed to capture the entire sky in some visible wavelength bands while the spacecraft pass through the comet's coma. EnVisS optical head is composed of a fisheye lens with a field of view of 180° x 40° coupled with an imaging detector equipped with both band-pass and polarimetric filters. The design of fisheye lenses requires to take into account some issues typical of very wide-angle lenses. The fundamental origin of the optical problems resides on the entrance pupil shift at large angle, where the paraxial approximation is no more valid: chief rays angles on the object side are not preserved passing through the optics preceding the aperture stop (fore-optics). This effect produces an anamorphic deformation of the image on the focal plane, i.e. the focal length is changing along the elevation angles. Tracing the rays appropriately requires some effort by the designer. It has to be considered that distortion, including anamorphism, is an aberration that does not affect the quality of a point source image, thus it can be present also in well corrected lenses. In this paper the optical design of the fisheye lens, that will be mounted on the EnVisS camera for the ESA F-class "Comet Interceptor" mission, will be presented together with the initial optical requirements and the final expected optical performances

The optical head of the EnVisS camera for the Comet Interceptor ESA mission: Phase 0 study

EnVisS (Entire Visible Sky) is an all-sky camera specifically designed to fly on the space mission Comet Interceptor. This mission has been selected in June 2019 as the first European Space Agency (ESA) Fast mission, a modest size mission with fast implementation. Comet Interceptor aims to study a dynamically new comet, or interstellar object, and its launch is scheduled in 2029 as a companion to the ARIEL mission. The mission study phase, called Phase 0, has been completed in December 2019, and then the Phase A study had started. Phase A will last for about two years until mission adoption expected in June 2022. The Comet Interceptor mission is conceived to be composed of three spacecraft: spacecraft A devoted to remote sensing science, and the other two, spacecraft B1 and B2, dedicated to a fly-by with the comet. EnVisS will be mounted on spacecraft B2, which is foreseen to be spin-stabilized. The camera is developed with the scientific task to image, in push-frame mode, the full comet coma in different colors. A set of ad-hoc selected broadband filters and polarizers in the visible range will be used to study the full scale distribution of the coma gas and dust species. The camera configuration is a fish-eye lens system with a FoV of about 180°x45°. This paper will describe the preliminary EnVisS optical head design and analysis carried out during the Phase 0 study of the mission

Neonatal programming by immunological challenge: effects on ovarian function in the adult rat

Neonatal exposure to an immunological challenge (lipopolysaccharide, LPS) increases the activity of hypothalamo-pituitary–adrenal axis and sensitises the GNRH pulse generator to the inhibitory influence of stress in adult rats. We investigated the effects of neonatal exposure to LPS on various reproductive parameters during puberty and into adulthood in female rats. LPS (50 μg/kg, i.p.) or saline was administered on postnatal days 3 and 5. Vaginal opening was recorded, and oestrous cyclicity was monitored immediately post puberty and again at 8–9 weeks of age. At 10 weeks of age, the ovaries were removed and the number of follicles was counted, together with the thickness of the theca interna of the largest antral follicles. Ovarian sympathetic nerve activity was assessed immunohistochemically by measurement of the levels of ovarian low-affinity receptor of nerve growth factor (p75NGFR). In rats exposed to LPS in early life, there was a significant delay in puberty and disruption of oestrous cyclicity immediately post puberty, which persisted into adulthood. The follicle reserve was decreased, the thickness of the theca interna increased and the expression profile of ovarian p75NGFR increased in the neonatal LPS-treated animals. These data suggest that exposure to LPS during early neonatal life can have long-term dysfunctional effects on the female reproductive system, which might involve, at least in part, increased ovarian sympathetic nerve activity

The Effect of Body Size on Countermovement Jump Kinetics in Children aged 7 to 11 years

The purpose this study was to examine the effect of body size oncountermovement jump (CMJ)kinetics in children.Participants(n = 160) aged 7-11 years, divided equally by sex and into primary school year groups(years 3, 4, 5 and 6), each performedone CMJ on aforce platform. The variables bodyweight(BW), peak force (Fmax), in-jump minimum force (IMF), in-jump vertical force range (IFR) and basic rate of force development (BRFD)wereattained from the force-time history and then subsequently scaled to account for body size. A significant age, sex and interaction effect werefound for theabsolutevariables BW, IMF, Fmaxand IFR (P 0.05). No significant age or sex differences were observed for normalised or allometrically scaled values(P > 0.05). The results indicate thatgirls and boys can be grouped together but that body size must be accounted for to enable accurate conclusions to be drawn independent of growth.Bodysizesignificantlyeffects the representation of CMJ kinetic results and therefore, future studies should report both absolute and scaled values.Future research should developan age-appropriate criterion method for children in order to determine processed CMJ variables to further investigate neuromuscular performance of children

Socioeconomic predictors and consequences of depression among primary care attenders with non-communicable diseases in the Western Cape, South Africa:Cohort study within a randomised trial

Background: Socioeconomic predictors and consequences of depression and its treatment were investigated in 4393 adults with specified non-communicable diseases attending 38 public sector primary care clinics in the Eden and Overberg districts of the Western Cape, South Africa.   Methods: Participants were interviewed at baseline in 2011 and 14 months later, as part of a randomised controlled trial of a guideline-based intervention to improve diagnosis and management of chronic diseases. The 10-item Center for Epidemiologic Studies Depression Scale (CESD-10) was used to assess depression symptoms, with higher scores representing more depressed mood. Results: Higher CESD-10 scores at baseline were independently associated with being less educated (p=0.004) and having lower income (p=0.003). CESD-10 scores at follow-up were higher in participants with less education (p=0.010) or receiving welfare grants (p=0.007) independent of their baseline scores. Participants with CESD-10 scores of 10 or more at baseline (56% of all participants) had 25% higher odds of being unemployed at follow-up (p=0.016), independently of baseline CESD-10 score and treatment status. Among participants with baseline CESD-10 scores of 10 or more, antidepressant medication at baseline was independently more likely in participants who had more education (p=0.002), higher income (p<0.001), or were unemployed (p=0.001). Antidepressant medication at follow up was independently more likely in participants with higher income (p=0.023), and in clinics with better access to pharmacists (p=0.053) and off-site drug delivery (p=0.013).  Conclusions: Socioeconomic disadvantage appears to be both a cause and consequence of depression, and may also be a barrier to treatment. There are opportunities for improving the prevention, diagnosis and treatment of depression in primary care in inequitable middle income countries like South Africa.  Trial registration: The trial is registered with Current Controlled Trials (ISRCTN20283604) and the Office for Human Research Protections Database (IRB00001938, FWA00001637)

Gas Accretion and Galactic Chemical Evolution: Theory and Observations

This chapter reviews how galactic inflows influence galaxy metallicity. The goal is to discuss predictions from theoretical models, but particular emphasis is placed on the insights that result from using models to interpret observations. Even as the classical G-dwarf problem endures in the latest round of observational confirmation, a rich and tantalizing new phenomenology of relationships between $M_*$, $Z$, SFR, and gas fraction is emerging both in observations and in theoretical models. A consensus interpretation is emerging in which star-forming galaxies do most of their growing in a quiescent way that balances gas inflows and gas processing, and metal dilution with enrichment. Models that explicitly invoke this idea via equilibrium conditions can be used to infer inflow rates from observations, while models that do not assume equilibrium growth tend to recover it self-consistently. Mergers are an overall subdominant mechanism for delivering fresh gas to galaxies, but they trigger radial flows of previously-accreted gas that flatten radial gas-phase metallicity gradients and temporarily suppress central metallicities. Radial gradients are generically expected to be steep at early times and then flattened by mergers and enriched inflows of recycled gas at late times. However, further theoretical work is required in order to understand how to interpret observations. Likewise, more observational work is needed in order to understand how metallicity gradients evolve to high redshifts.Comment: Invited review to appear in Gas Accretion onto Galaxies, Astrophysics and Space Science Library, eds. A. J. Fox & R. Dav\'e, to be published by Springer. 29 pages, 2 figure

Multiproxy summer and winter surface air temperature field reconstructions for southern South America covering the past centuries

We statistically reconstruct austral summer (winter) surface air temperature fields back to ad 900 (1706) using 22 (20) annually resolved predictors from natural and human archives from southern South America (SSA). This represents the first regional-scale climate field reconstruction for parts of the Southern Hemisphere at this high temporal resolution. We apply three different reconstruction techniques: multivariate principal component regression, composite plus scaling, and regularized expectation maximization. There is generally good agreement between the results of the three methods on interannual and decadal timescales. The field reconstructions allow us to describe differences and similarities in the temperature evolution of different sub-regions of SSA. The reconstructed SSA mean summer temperatures between 900 and 1350 are mostly above the 1901-1995 climatology. After 1350, we reconstruct a sharp transition to colder conditions, which last until approximately 1700. The summers in the eighteenth century are relatively warm with a subsequent cold relapse peaking around 1850. In the twentieth century, summer temperatures reach conditions similar to earlier warm periods. The winter temperatures in the eighteenth and nineteenth centuries were mostly below the twentieth century average. The uncertainties of our reconstructions are generally largest in the eastern lowlands of SSA, where the coverage with proxy data is poorest. Verifications with independent summer temperature proxies and instrumental measurements suggest that the interannual and multi-decadal variations of SSA temperatures are well captured by our reconstructions. This new dataset can be used for data/model comparison and data assimilation as well as for detection and attribution studies at sub-continental scale